Match Analysis: Arizona Cardinals vs San Francisco 49ers – Prediction

Match Details

• Date: 2025-11-16
• Time: 9:05 PM UTC
• Location: State Farm Stadium, Arizona

Game Overview

The San Francisco 49ers (6-4) visit the Arizona Cardinals (3-6) in a crucial NFC West clash. The 49ers seek to maintain momentum after recent recovery from losses, while the Cardinals aim to leverage home advantage despite a poor season record.

Key Factors to Consider

• 49ers are 6-4 overall and have covered the spread in their last four games following a loss. Cardinals are 3-6, struggling against winning teams and have a poor 1-3 home record this season.
• 49ers have dominated recent matchups, winning 4 of last 5 vs Cardinals. Cardinals have found some success as underdogs, covering in 9 of last 10 games after a loss, but have lost 8 straight to teams with winning records.
• No major injuries reported on either side that significantly alter starting lineups or depth charts as of current data.
• Game played at Cardinals' home stadium where 49ers have historically struggled on Sundays (lost 9 of last 10), but recent form for 49ers on road is positive.
• 49ers motivated to sustain playoff push and rebound after losses; Cardinals appear resigned to missing playoffs, which may reduce competitive edge.

Odds and Predictions

Predicted Outcome

San Francisco 49ers moneyline win

Predicted Score: San Francisco 49ers 27, Arizona Cardinals 20

Match Analysis: Seattle Seahawks vs Arizona Cardinals – Prediction

Match Details

• Date: 2025-11-09
• Time: 9:05 PM UTC
• Location: Lumen Field, Seattle, Washington

Game Overview

The Seattle Seahawks host the Arizona Cardinals in a crucial NFC West matchup with Seattle favored to win by 6.5 points. The Seahawks carry momentum on a three-game winning streak, holding a strong home record (6-2) versus the Cardinals' struggling 3-5 away performance.

Key Factors to Consider

• Seahawks have been strong at home and on a three-game win streak, showcasing solid offense and defense; Cardinals are inconsistent with a poor road record and multiple recent losses.
• Recent meetings favor Seattle, with last matchup scoring a combined 43 points; Seahawks generally outperform Cardinals at home.
• No major injuries reported for Seahawks; Cardinals have key players questionable but not confirmed out, impacting offensive stability.
• Seattle benefits from home-field advantage and favorable weather conditions for their play style; no significant travel or scheduling disruptions.
• Seahawks motivated to extend winning streak and solidify playoff positioning; Cardinals aiming to rebound from disappointing start but face uphill task on road.

Odds and Predictions

Predicted Outcome

Seattle Seahawks to win straight up (moneyline), cover the -6.5 spread, with total points over 44.5

Predicted Score: Seattle Seahawks 31 – Arizona Cardinals 17

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Match Analysis: Dallas Cowboys vs Arizona Cardinals – Prediction

Match Details

• Date: 2025-11-03
• Time: 1:15 AM UTC
• Location: AT&T Stadium

Game Overview

The Dallas Cowboys host the Arizona Cardinals in a Week 9 NFL matchup. Dallas enters with a 3-4-1 record, while Arizona is 2-5. The Cowboys are favored at home, with the line set at -2.5 and the total at 54.5 points. Both teams have shown offensive volatility, but Dallas has a clear edge in recent form and home-field advantage.

Key Factors to Consider

• Dallas has shown resilience at home (2-0-1), while Arizona has struggled on the road (1-2). The Cowboys have averaged 24.3 points per game, while Arizona has managed just 20.1. Dallas’s offense is more balanced, and their defense has been more consistent, especially in the red zone.
• Dallas has dominated recent meetings, winning 5 of the last 6 matchups. The Cowboys have covered the spread in 4 of those 6 games, including a 31-14 win in their last meeting.
• No major injuries reported for either team. Both Kyler Murray and Dak Prescott are expected to start, providing full offensive firepower.
• The game is at AT&T Stadium, where Dallas has a strong home record. Weather is expected to be mild, with no significant impact on play.
• Dallas is fighting to stay in playoff contention, while Arizona is looking to avoid a losing streak. The Cowboys have more to play for, especially with a tough schedule ahead.

Odds and Predictions

Predicted Outcome

Dallas Cowboys to win and cover the spread, with the game going over the total.

Predicted Score: Dallas Cowboys 31, Arizona Cardinals 24

Match Analysis: Arizona Cardinals vs Green Bay Packers – Prediction

Match Details

• Date: 2025-10-19
• Time: 8:25 PM UTC
• Location: Arizona Cardinals Home Stadium

Game Overview

The Green Bay Packers visit the Arizona Cardinals in a Week 7 NFL matchup. The Packers enter as solid favorites with a strong NFC North standing and better recent form, while the Cardinals have shown resilience as underdogs and have covered the spread multiple times this season.

Key Factors to Consider

• Packers hold a 3-1-1 record atop the NFC North and have been consistent against the spread, while Cardinals are 3-3 ATS with a tendency to cover as underdogs by 6.5 points or more.
• Historically competitive matchups without overwhelming dominance; recent data shows Packers favored but with challenges covering sizeable spreads against the Cardinals.
• No significant injuries reported for either side that materially impact starting offensive or defensive units at this time.
• Game played at Arizona's home venue provides Cardinals a home-field advantage; weather and travel conditions favor the home team.
• Packers motivated by strong division positioning and playoff prospects; Cardinals motivated to upset a divisional front-runner at home.

Odds and Predictions

Predicted Outcome

Packers to win on the moneyline, Cardinals to cover the spread, and game total to go over 44.5 points.

Predicted Score: Packers 27 – Cardinals 23

Match Analysis: Indianapolis Colts vs Arizona Cardinals – Prediction

Match Details

• Date: 2025-10-12
• Time: 5:01 PM UTC
• Location: Lucas Oil Stadium, Indianapolis, IN

Game Overview

The 4-1 Indianapolis Colts, riding high with a dominant offense and unbeaten home record, host the 2-3 Arizona Cardinals, who enter on a three-game losing streak and face uncertainty at QB. The Colts are heavy favorites as both teams look to solidify postseason positioning midway through the NFL season.

Key Factors to Consider

• Colts are 4-1, averaging over 32 points per game and coming off a 40-6 blowout win. Cardinals are 2-3, struggling offensively, and have lost three straight, including a recent upset as heavy favorites. Colts are 3-0 at home; Cardinals are 1-1 on the road.[1][2][5]
• No recent head-to-head data provided; this is an interconference matchup with minimal recent history.
• Cardinals face injury turmoil, including uncertainty around QB Kyler Murray. Colts' offense appears healthy and firing on all cylinders.[2]
• No notable external factors (weather, travel, etc.) reported; Lucas Oil Stadium’s retractable roof neutralizes weather concerns.[2]
• Colts are in a tight divisional race (tied for 1st in AFC South) and motivated to protect home-field advantage. Cardinals are desperate to snap their skid and stay in the NFC West hunt, but recent form and injuries dampen optimism.[2][5]

Odds and Predictions

Predicted Outcome

The Colts are the clear superior team in form, health, and momentum. Expect Indianapolis to control the game on both sides of the ball, covering the spread in a relatively low-scoring affair as Arizona’s struggling offense fails to keep pace.

Predicted Score: Colts 27 – Cardinals 17

Match Analysis: Arizona Cardinals vs Seattle Seahawks – Prediction

Match Details

• Date: 2025-09-26
• Time: 12:16 AM UTC
• Location: Arizona Cardinals Home Stadium

Game Overview

The Arizona Cardinals and Seattle Seahawks both enter Week 4 with 2-1 records, facing off at the Cardinals' home turf. The matchup is expected to be competitive with close odds and balanced recent performances, setting the stage for a tightly contested NFC West clash.

Key Factors to Consider

• Both teams are 2-1. Cardinals have demonstrated strong offensive output recently, notably a dominant 44-13 win over New Orleans and a 31-17 away victory in Pittsburgh. Seahawks also perform well but slightly behind in scoring potency. The Cardinals have home field advantage, which historically benefits their performance.
• Recent head-to-head matchups suggest a fairly even rivalry with slight edge to Seahawks in situational factors. However, as the game is in Arizona, the Cardinals tend to perform better at home against Seattle.
• No major injuries reported for either team impacting starters or key positions, allowing both squads to field near full strength.
• Thursday night prime-time slot adds pressure and excitement, favoring the team better at handling spotlight. Arizona's recent home performances under prime time have been solid. Weather expected to be fair, neutralizing external environmental impact.
• Both teams are NFC West rivals fighting for divisional positioning; motivation is high. The Cardinals seek to capitalize on home advantage to maintain momentum; Seahawks aim to steal a divisional win on the road.

Odds and Predictions

Predicted Outcome

Arizona Cardinals moneyline -115, -1.5 spread, and under 43.5 total points

Predicted Score: Arizona Cardinals 24 – Seattle Seahawks 20

Match Analysis: San Francisco 49ers vs Arizona Cardinals – Prediction

Match Details

• Date: 2025-09-21
• Time: 8:26 PM UTC
• Location: Levi's Stadium, Santa Clara, California

Game Overview

A tightly contested NFC West divisional matchup between two undefeated teams with strong defenses and capable offenses. The 49ers enter favored at home by a narrow margin versus the Cardinals who have recent success against them in head-to-head matchups.

Key Factors to Consider

• Both teams are 2-0 with solid recent wins; 49ers show balanced offense with 344 yards last game and solid defense; Cardinals have won last two meetings convincingly and boast a strong running and passing attack.
• Cardinals have won last two meetings including a 47-24 road win; overall H2H in last 10 is balanced at 5-5.
• No major injury reports impacting key starters disclosed prior to game, both teams expected near full strength.
• Game played at Levi's Stadium benefits the 49ers' home advantage; weather not expected to be a factor.
• Both teams motivated to maintain perfect records early in season and gain divisional edge; recent psychological edge to Cardinals from last two wins.

Odds and Predictions

Predicted Outcome

Arizona Cardinals moneyline upset win given momentum and favorable head-to-head, with moderate confidence to back this undervalued line; expect moderately high scoring game.

Predicted Score: Cardinals 27 – 49ers 24

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Match Analysis: Arizona Cardinals vs Carolina Panthers – Prediction

Match Details

• Date: 2025-09-14
• Time: 8:05 PM UTC
• Location: State Farm Stadium

Game Overview

The Arizona Cardinals (1-0) host the Carolina Panthers (0-1) in an early NFC matchup. The Cardinals are favored strongly due to a better start, home advantage, and superior recent offensive efficiency, while the Panthers are adjusting with a young QB Bryce Young who showed potential despite a loss in Week 1.

Key Factors to Consider

• Cardinals have started the season 1-0 with a solid offensive output (358.2 yards per game) and improved protection for QB Kyler Murray. Panthers were 0-1, struggling defensively last game and relying on rookie QB Bryce Young who showed mobility but inconsistency.
• Recent H2H favors Arizona with a win probability edge, reflecting better execution and home advantage. No significant recent draws; Arizona has covered spreads against Carolina in most recent meetings.
• No critical injuries reported on either side affecting key skill positions or starters as of current updates, enhancing confidence in starting lineups.
• Home crowd support for Arizona at State Farm Stadium and early-season motivation to establish divisional dominance favor Cardinals. Weather conditions expected to be clear, neutral to game flow.
• Arizona pursues a 2-0 start to cement playoff credentials and build momentum amid a tough NFC West race. Carolina aims to rebound from opening loss and prove rookie QB competency, but motivation is tempered by early season rebuilding phase.

Odds and Predictions

Predicted Outcome

Arizona Cardinals to win straight up, cover the -6.5 spread, with the total going Over 44.5 points.

Predicted Score: Arizona Cardinals 30, Carolina Panthers 17