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Chicago Cubs vs. St. Louis Cardinals Prediction MLB in Baseball

Match Analysis: Chicago Cubs vs St. Louis Cardinals – Prediction

Match Details

  • Date: 2025-09-28
  • Time: 7:20 PM UTC
  • Location: Wrigley Field

Game Overview

The Chicago Cubs host the St. Louis Cardinals in a late September MLB regular-season game. The Cubs have a superior record and hosting advantage, while the Cardinals are struggling with a sub-.500 away performance. The starting pitchers are Jameson Taillon for the Cubs (11-7, 3.68 ERA) and Michael McGreevy for the Cardinals (8-4, 4.52 ERA).

Key Factors to Consider

  • The Cubs hold a strong 91-70 overall record with good home performance (49-31), while the Cardinals are 78-83 overall and weaker on the road (34-46). Cubs have better pitching and more consistent late-season form.
  • Recent meetings favor the Cubs, who have outscored the Cardinals with solid offensive output, especially at home. The Cubs have won multiple recent games against the Cardinals this season.
  • No major injuries reported for either side affecting starting pitchers or key hitters, maintaining relatively full-strength rosters.
  • Weather conditions at Wrigley Field are normal for late September with no significant impact expected. The Cubs benefit from playing at home with strong fan support.
  • The Cubs are pushing for playoff positioning, motivated to secure wins down the stretch. Cardinals have less playoff pressure and have shown inconsistency, possibly lowering motivation.

Odds and Predictions

Category Odds Prediction Confidence
Moneyline Cubs -169, Cardinals +144 Chicago Cubs ★★★★☆ 78%
Spread Cubs -1.5 at +128, Cardinals +1.5 at -151 Chicago Cubs -1.5 ★★★★☆ 72%
Over/under Over 8 -111, Under 8 -110 Over 8 runs ★★★☆☆ 65%

Top EV Betting Odds

Discover the best value bets based on our EV analysis.

Market EV Pick
Moneyline Chicago Cubs -1%
Spread N/A
Over/Under Over 8 10%

🔥 Best Value Pick: Over 8 at 10% EV | Suggested Bet Size: 11.4% (Kelly Criterion)

Predicted Outcome

Chicago Cubs to win outright (moneyline), cover the -1.5 run spread, and the total runs to go over 8.

Predicted Score: Chicago Cubs 5 – St. Louis Cardinals 3


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San Francisco Giants vs. St. Louis Cardinals Prediction MLB in Baseball

Match Analysis: San Francisco Giants vs St. Louis Cardinals – Prediction

Match Details

  • Date: 2025-09-25
  • Time: 1:45 AM UTC
  • Location: Oracle Park, San Francisco, CA

Game Overview

MLB regular season late September matchup between San Francisco Giants and St. Louis Cardinals with both teams holding losing records but playing for pride and potential late-season evaluation.

Key Factors to Consider

  • Both teams have identical 77-80 records showing middling performance; Giants have a slight edge in home performance, Cardinals have inconsistent away results. Giants' Robbie Ray (ERA 3.65) faces Cardinals' Sonny Gray (ERA 4.33), giving Giants an edge on the mound.
  • Recent H2H meetings have been competitive; no dominant trend but Giants have slight home advantage historically.
  • No major injuries reported for either team impacting starting pitchers or key lineup hitters, suggesting both lineups near full strength.
  • Late September weather at Oracle Park typically mild, minimal impact expected. No significant travel or fatigue concerns for either team.
  • Both teams eliminated from playoff contention; motivation expected to be average, focusing on player development and season closure pride.

Odds and Predictions

Category Odds Prediction Confidence
Moneyline -110 San Francisco Giants ★★★☆☆ 65%
Spread -194 San Francisco Giants -1.5 ★★★☆☆ 60%
Over/under -122 Under 7.5 ★★★☆☆ 62%

Top EV Betting Odds

Discover the best value bets based on our EV analysis.

Market EV Pick
Moneyline San Francisco Giants 9%
Spread N/A
Over/Under Under 7.5 24%

🔥 Best Value Pick: Under 7.5 at 24% EV | Suggested Bet Size: 24% (Kelly Criterion)

Predicted Outcome

San Francisco Giants moneyline

Predicted Score: San Francisco Giants 4 – 2 St. Louis Cardinals


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Top EV Parlay for Baseball – September 24, 2025 Daily Parlay

Top EV Parlay for Baseball – September 24, 2025

Game Pick Odds EV
New York Yankees vs. Chicago White Sox Prediction New York Yankees -375 212%
Oakland Athletics vs. Houston Astros Prediction Under 9 -106 26%
San Francisco Giants vs. St. Louis Cardinals Prediction Under 7.5 100 24%

Combined Odds: +392 |
Wager: $20 —
Potential Payout: $98.47

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Top EV Parlay for Baseball – September 22, 2025 Daily Parlay

Top EV Parlay for Baseball – September 22, 2025

Game Pick Odds EV
San Francisco Giants vs. St. Louis Cardinals Prediction Under 7.5 105 23%
Atlanta Braves vs. Washington Nationals Prediction Under 7 100 20%
San Diego Padres vs. Milwaukee Brewers Prediction Under 7 -104 12%

Combined Odds: +704 |
Wager: $20 —
Potential Payout: $160.85

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3 Pick Parlay for Baseball – September 22, 2025 Daily Parlay

3 Pick Daily Parlay

Game Pick Odds (American) Confidence
Atlanta Braves vs. Washington Nationals Prediction Atlanta Braves Win -260 ★★★★☆ 78% (78%)
San Francisco Giants vs. St. Louis Cardinals Prediction San Francisco Giants Win -138 ★★★★☆ 70% (70%)
San Diego Padres vs. Milwaukee Brewers Prediction San Diego Padres Win -130 ★★★☆☆ 67% (67%)

Parlay Odds Calculation

Combined American Odds: +322

Wager: $20 — Potential Payout: $84.5

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St. Louis Cardinals vs. Milwaukee Brewers Prediction MLB in Baseball

Match Analysis: St. Louis Cardinals vs Milwaukee Brewers – Prediction

Match Details

  • Date: 2025-09-21
  • Time: 6:16 PM UTC
  • Location: Busch Stadium

Game Overview

The Milwaukee Brewers, holding a strong 95-60 record and currently on the road, face the St. Louis Cardinals, who have a disappointing 75-80 record. The Brewers are favored on the moneyline and the spread, reflecting superior recent form and pitching. The total runs line is set at 9, reflecting a moderately high-scoring expectation.

Key Factors to Consider

  • Brewers have been strong this season with a 95-60 record, winning 65.2% of games as favorites and posting an 85-66 record against the spread. Cardinals have struggled with a sub-.500 record and poor recent form.
  • Brewers have had the upper hand in the series, with predictions heavily favoring Milwaukee to take this matchup.
  • Milwaukee has minor injuries with W. Contreras and M. Winn listed; Cardinals deal with injuries to key players like C. Thomas and G. Mitchell, weakening their lineup.
  • Game played at Busch Stadium favors Cardinals slightly, but Brewers' stronger lineup and pitching depth likely offset home advantage.
  • Milwaukee is pushing to consolidate their higher standing and playoff position, while Cardinals have less motivation with a losing record and likely out of contention.

Odds and Predictions

Category Odds Prediction Confidence
Moneyline Milwaukee -136, St. Louis +116 Milwaukee Brewers ★★★★☆ 74%
Spread Milwaukee -1.5 +126, St. Louis +1.5 -152 Milwaukee Brewers -1.5 ★★★☆☆ 68%
Over/under Over 9 -105, Under 9 -115 Over 9 runs ★★★☆☆ 60%

Top EV Betting Odds

Discover the best value bets based on our EV analysis.

Market EV Pick
Moneyline Milwaukee Brewers -6%
Spread N/A
Over/Under Over 9 17%

🔥 Best Value Pick: Over 9 at 17% EV | Suggested Bet Size: 18% (Kelly Criterion)

Predicted Outcome

Milwaukee Brewers to win on the moneyline, cover the -1.5 run spread, and the game to go over 9 runs total.

Predicted Score: Milwaukee Brewers 6 – St. Louis Cardinals 4


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St. Louis Cardinals vs. Cincinnati Reds Prediction MLB in Baseball

Match Analysis: St. Louis Cardinals vs Cincinnati Reds – Prediction

Match Details

  • Date: 2025-09-17
  • Time: 5:15 PM UTC
  • Location: Busch Stadium, St. Louis

Game Overview

This is a late-season crucial MLB matchup between the Cincinnati Reds and the St. Louis Cardinals. Both teams are fighting for playoff relevance, with the Reds sitting three games behind the final NL wild-card spot and the Cardinals having minimal postseason chances. Pitching matchups and recent form are critical factors.

Key Factors to Consider

  • The Reds have lost four of their last five games and are under pressure to win to stay in wild-card contention; their offense has cooled recently. The Cardinals are slightly below .500 overall but have a better home record, though with negligible playoff likelihood.
  • Brady Singer (Reds) has a strong recent record against the Cardinals with a 2.50 ERA in three starts this year. The Cardinals' pitcher has shown shakiness recently compared to Singer's consistent form.
  • No critical injuries affecting starting pitchers reported. Some minor injuries on Cardinals’ roster but none impacting the starting lineup or pitching staff significantly.
  • The game is at Busch Stadium, where Cardinals tend to perform better. Weather and other external factors are stable and expected not to influence play materially.
  • Cincinnati’s must-win playoff push gives them higher motivation, whereas the Cardinals have little postseason motivation remaining.

Odds and Predictions

Category Odds Prediction Confidence
Moneyline Cincinnati Reds -113, St. Louis Cardinals +103 Cincinnati Reds ★★★★☆ 72%
Spread Cincinnati Reds -1.5 +145, St. Louis Cardinals +1.5 -165 Cincinnati Reds -1.5 ★★★☆☆ 65%
Over/under Over 8.5 -110, Under 8.5 -110 Under 8.5 ★★★☆☆ 68%

Top EV Betting Odds

Discover the best value bets based on our EV analysis.

Market EV Pick
Moneyline Cincinnati Reds 6%
Spread N/A
Over/Under Under 8.5 15%

🔥 Best Value Pick: Under 8.5 at 15% EV | Suggested Bet Size: 16% (Kelly Criterion)

Predicted Outcome

Cincinnati Reds to win on the moneyline, covering the spread, with the game total finishing under 8.5 runs.

Predicted Score: Reds 5, Cardinals 3


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Top EV Parlay for Baseball – September 16, 2025 Daily Parlay

Top EV Parlay for Baseball – September 16, 2025

Game Pick Odds EV
Colorado Rockies vs. Miami Marlins Prediction Over 10 -112 17%
Kansas City Royals vs. Seattle Mariners Prediction Under 8.5 -115 16%
St. Louis Cardinals vs. Cincinnati Reds Prediction Over 8 -105 13%

Combined Odds: +591 |
Wager: $20 —
Potential Payout: $138.18

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Milwaukee Brewers vs. St. Louis Cardinals Prediction MLB in Baseball

Match Analysis: Milwaukee Brewers vs St. Louis Cardinals – Prediction

Match Details

  • Date: 2025-09-14
  • Time: 6:10 PM UTC
  • Location: American Family Field, Milwaukee

Game Overview

Milwaukee Brewers (98-63) host the St. Louis Cardinals (77-82) in a critical NL Central matchup. Brewers are pushing toward the playoffs with a dominant bullpen and better overall offense, while the Cardinals have struggled and show inconsistency, especially in pitching.

Key Factors to Consider

  • Brewers have a significantly better record and recent form, with strong pitching from Jose Quintana and a powerful offense. Cardinals are below .500 and inconsistent, especially in starting pitching.
  • Brewers have dominated recent meetings and hold a psychological edge. They also benefit from home-field advantage.
  • No major injuries reported for Brewers; Cardinals dealing with some pitching inconsistencies, less depth in bullpen.
  • Home crowd and stadium factors favor Brewers. Weather and playing conditions likely to be normal with no adverse effects.
  • Brewers motivated to secure playoff positioning while Cardinals are out of contention, reducing their intensity.

Odds and Predictions

Category Odds Prediction Confidence
Moneyline -178 Milwaukee Brewers ★★★★☆ 79%
Spread +115 Milwaukee Brewers -1.5 ★★★★☆ 75%
Over/under -105 Under 8.5 ★★★☆☆ 62%

Top EV Betting Odds

Discover the best value bets based on our EV analysis.

Market EV Pick
Moneyline Milwaukee Brewers 6%
Spread N/A
Over/Under Under 8.5 21%

🔥 Best Value Pick: Under 8.5 at 21% EV | Suggested Bet Size: 22.1% (Kelly Criterion)

Predicted Outcome

Milwaukee Brewers to win and cover the -1.5 run line, with a final score favoring Milwaukee comfortably.

Predicted Score: Milwaukee Brewers 5 – St. Louis Cardinals 2


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Top EV Parlay for Baseball – September 13, 2025 Daily Parlay

Top EV Parlay for Baseball – September 13, 2025

Game Pick Odds EV
Boston Red Sox vs. New York Yankees Prediction New York Yankees -137 32%
Washington Nationals vs. Pittsburgh Pirates Prediction Under 8.5 105 27%
Milwaukee Brewers vs. St. Louis Cardinals Prediction Under 7.5 100 24%

Combined Odds: +609 |
Wager: $20 —
Potential Payout: $141.85

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