Match Analysis: Chicago Cubs vs St. Louis Cardinals – Prediction

Match Details

• Date: 2025-09-28
• Time: 7:20 PM UTC
• Location: Wrigley Field, Chicago

Game Overview

The Chicago Cubs will host the St. Louis Cardinals in a critical late-season MLB matchup. The Cubs recently dominated the Cardinals 12-1 in their last encounter on September 26, 2025, showcasing strong offensive firepower highlighted by multiple home runs and a grand slam. This game is pivotal for both teams as they jockey for playoff positioning.

Key Factors to Consider

• The Cubs are in strong form, having just delivered a dominant 12-1 victory over the Cardinals with exceptional hitting performances including Pete Crow-Armstrong's milestone achievement (30 homers, 30 doubles, 30 stolen bases). The Cardinals showed some resilience but were unable to contain the Cubs' offence.
• In the last head-to-head meeting on September 26, 2025, the Cubs routed the Cardinals 12-1 at Wrigley Field. Historically, these divisional rivals play tightly contested games, but the recent game heavily favors the Cubs' current momentum.
• Current injury data for both teams is not explicitly provided in the sources, implying no major reported absences impacting either side significantly for this match.
• The match is at Wrigley Field, which is traditionally favorable for the Cubs. Weather or other external effects are not specified. Fan Appreciation Weekend promotions could add motivation for the home crowd and team.
• Both teams are fighting for playoff positioning in late September with high stakes. The Cubs' recent confident win over the Cardinals likely boosts their morale, while the Cardinals will be motivated to avoid back-to-back losses against a division rival.

Odds and Predictions

Predicted Outcome

Chicago Cubs are favored to win given their recent dominant performance and home field advantage. The moneyline and spread odds also signal market confidence in the Cubs overcoming the Cardinals decisively.

Predicted Score: Chicago Cubs 7 – St. Louis Cardinals 3

3 Pick Daily Parlay

Parlay Odds Calculation

Combined American Odds: +660

Wager: $20 — Potential Payout: $151.96

Match Analysis: San Francisco Giants vs St. Louis Cardinals – Prediction

Match Details

• Date: 2025-09-25
• Time: 1:45 AM UTC
• Location: Oracle Park, San Francisco, CA

Game Overview

The St. Louis Cardinals visit the San Francisco Giants in a late September MLB matchup. Both teams appear to be out of playoff contention with records near .500, making this game important for ending the season on a high note and gaining momentum.

Key Factors to Consider

• San Francisco Giants hold a slightly better home record (38-39) compared to the Cardinals' away record (34-43). Recent form and player health could influence the game outcome, with Giants favored slightly per odds.
• Season head to head data shows a closely matched rivalry with Giants holding a marginal edge at home, but the Cardinals have taken some wins on the road recently.
• No specific injury data available from latest sources; however, given late season, fatigue and minor injuries could impact bullpen depth and starting rotations.
• Game held at Oracle Park, known for pitcher-friendly conditions. Weather not specified but typical late September fog and cooler temps could suppress offense.
• With both teams outside playoff spots, motivation may focus on ending the season strong and evaluating players for next season.

Odds and Predictions

Predicted Outcome

San Francisco Giants are predicted to edge out the St. Louis Cardinals with their home park advantage and slightly better recent performance.

Predicted Score: San Francisco Giants 4 – St. Louis Cardinals 3

3 Pick Daily Parlay

Parlay Odds Calculation

Combined American Odds: +389

Wager: $20 — Potential Payout: $97.88

Top EV Parlay for Baseball – September 22, 2025

Combined Odds: +704 |
Wager: $20 —
Potential Payout: $160.85

Match Analysis: St. Louis Cardinals vs Milwaukee Brewers – Prediction

Match Details

• Date: 2025-09-21
• Time: 6:16 PM UTC
• Location: Busch Stadium, St. Louis, Missouri

Game Overview

The Milwaukee Brewers visit the St. Louis Cardinals for Game 3 of their series, with the series currently tied 1-1. Milwaukee (95-60) is favored given their stronger recent form, deeper lineup, and effective pitching, including the solid performance of their starter Peralta. St. Louis (75-80) is the underdog but playing at home in Busch Stadium offers some advantage.

Key Factors to Consider

• Milwaukee Brewers have a strong season record (95-60) and have a winning trend as favorites, winning 65.2% of 89 games as favorites, and 38-13 when favored at -136 or better on moneyline. They have an overall record against the spread of 85-66 and have played over totals 77 times this season. St. Louis Cardinals have a below .500 record (75-80) and are underdogs in this game.
• The current series is tied 1-1. Historical context points to Milwaukee’s advantage in pitching and depth. Specific head-to-head stats for this series favor Milwaukee but detailed historical win/loss records for this matchup in 2025 are limited.
• No significant or game-impacting injuries reported for either team affecting starting pitchers or key hitters in this game from available sources.
• Playing at Busch Stadium gives St. Louis the home field advantage, but Milwaukee’s momentum and favorable odds suggest confidence despite being the away team. Weather or other external factors were not reported as influencing this match notably.
• Milwaukee, with a strong record and likelihood to maintain playoff positioning, is highly motivated to secure a series win on the road. St. Louis, out of playoff contention with a losing record, may play with lower external pressure but higher motivation to upset favorites at home.

Odds and Predictions

Predicted Outcome

Milwaukee Brewers are favored to win considering their superior pitching, batting depth, and strong season performance. The predicted win probability for Milwaukee is around 54.4%. St. Louis may compete well at home but likelihood of victory is lower.

Predicted Score: Milwaukee Brewers 5 – St. Louis Cardinals 3

Match Analysis: St. Louis Cardinals vs Cincinnati Reds – Prediction

Match Details

• Date: 2025-09-17
• Time: 5:15 PM UTC
• Location: Busch Stadium, St. Louis, MO

Game Overview

The Cincinnati Reds (75-76, 3rd NL Central) visit the St. Louis Cardinals (74-78, 4th NL Central) in the decisive game of a three-game series. Both teams are near the bottom half of the division, with no playoff implications, but both will want to finish the season strongly. The Reds are slightly favored by bookmakers, reflected in the moneyline odds, but home-field advantage for the Cardinals and the series-decider context add intrigue[1][3].

Key Factors to Consider

• The Reds and Cardinals have performed similarly this season, both below .500 but with almost identical records. Neither team has shown a clear edge in recent form, and both are inconsistent, particularly in late-game situations.
• Recent head-to-head data is not provided in the search results, but both teams have struggled throughout the season, suggesting the series is likely close.
• No injury updates are available in the search results. This is a critical blind spot and is often a decisive factor in baseball games.
• Weather and venue are standard for this time of year in St. Louis. There are no notable external disruptions mentioned in the search results.
• With both teams out of playoff contention, motivation may be a factor, but pride, finishing above .500, and divisional rivalry remain. The series is tied, so the winner of this game takes the series—an added incentive for both rosters[3].

Odds and Predictions

Predicted Outcome

Given the tight margin in odds and near-identical records, the game is expected to be highly competitive. The Reds are a slight favorite, but the Cardinals have home-field advantage. The game could swing either way, but the Reds’ marginally better season and slight edge in the odds suggest a narrow preference for Cincinnati, though with low confidence.

Predicted Score: Cincinnati Reds 4, St. Louis Cardinals 3

Match Analysis: Milwaukee Brewers vs St. Louis Cardinals – Prediction

Match Details

• Date: 2025-09-14
• Time: 6:10 PM UTC
• Location: American Family Field, Milwaukee, WI

Game Overview

The final game of a 3-game MLB series between the Milwaukee Brewers and St. Louis Cardinals. The Brewers have the home-field advantage. The Brewers hold a strong 91-58 overall record with 48-26 at home, while the Cardinals struggle with a 72-77 overall record and 31-43 away. Recent games in the series have been close, with Brewers winning 3-2 in the latest match-up.

Key Factors to Consider

• Milwaukee Brewers have a superior season record and strong home performance compared to the Cardinals who have a losing record and a 5-game losing streak. Brewers' pitching has been solid with promising starter Misiorowski (5-2, 4.09 ERA). Cardinals' starter Mikolas (7-10, 4.84 ERA) shows less effectiveness. Brewers are currently on a 2-game winning streak, Cardinals on a 5-game losing streak.
• Recent head-to-head results in this series favor the Brewers narrowly with two wins (3-2 twice) compared to one win for the Cardinals (8-5). The series has been tightly contested, but Brewers show a slight edge in close games.
• No significant injury reports are available for either team that would impact starting lineups or pitching staff substantially for this game.
• The game is played at American Family Field with mild weather conditions (~73°F at 7 PM local). No external disruptions or major weather concerns are reported.
• Milwaukee is competing for playoff positioning and benefits from home advantage with a strong momentum. St. Louis is less motivated given their record and losing streak, but may strive to end the series with a win.

Odds and Predictions

Predicted Outcome

Milwaukee Brewers are favored to win given their stronger performance, home advantage, and more effective starting pitching. Expected to win by a narrow margin in a moderately low-scoring game.

Predicted Score: Milwaukee Brewers 4 – St. Louis Cardinals 2

3 Pick Daily Parlay

Parlay Odds Calculation

Combined American Odds: +379

Wager: $20 — Potential Payout: $95.83

Match Analysis: Seattle Mariners vs St. Louis Cardinals – Prediction

Match Details

• Date: 2025-09-11
• Time: 1:41 AM UTC
• Location: Seattle Mariners home field

Game Overview

Seattle Mariners and St. Louis Cardinals face each other after Mariners secured a 5-3 victory on September 9, 2025. Mariners are currently strong in their division race and coming off a performance led by Randy Arozarena's four RBIs including a crucial three-run homer. The Cardinals showed competitive offense but fell short again.

Key Factors to Consider

• The Mariners have momentum, winning the last matchup 5-3 with strong offensive contributions and solid pitching performance limiting Cardinals to 3 runs. Mariners are close to leading the AL West. The Cardinals have had good individual moments but have been less consistent, especially away from home.
• In their recent meeting on September 9, Mariners defeated Cardinals 5-3, covering the spread by winning with at least a 2-run margin, demonstrating a slight dominance in this short-term matchup.
• No current injury reports available from the data but Mariners likely fielding near full strength given recent performance; Cardinals injury status unknown but no major absences reported in recent games.
• Game played at Mariners’ home venue favors the Mariners due to home-field advantage. Weather and other external conditions were not mentioned, assumed neutral.
• Mariners are highly motivated to close their gap in the AL West, coming off a big win and looking to maintain momentum. Cardinals likely motivated to respond after back-to-back losses to Mariners and try to regain ground in their league.

Odds and Predictions

Predicted Outcome

Seattle Mariners are favored to win again based on recent form, home advantage, and bookmakers odds. Expect a moderately close game but Mariners with a clear edge.

Predicted Score: Seattle Mariners 6 – 4 St. Louis Cardinals