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3 Pick Parlay for American Football – September 21, 2025 Daily Parlay

3 Pick Daily Parlay

Game Pick Odds (American) Confidence
New York Giants vs. Kansas City Chiefs Prediction Kansas City Chiefs Win -325 β˜…β˜…β˜…β˜…β˜† 78% (78%)
Seattle Seahawks vs. New Orleans Saints Prediction Seattle Seahawks Win -375 β˜…β˜…β˜…β˜…β˜† 78% (78%)
Philadelphia Eagles vs. Los Angeles Rams Prediction Philadelphia Eagles Win -185 β˜…β˜…β˜…β˜…β˜† 78% (78%)

Parlay Odds Calculation

Combined American Odds: +155

Wager: $20 β€” Potential Payout: $51.04

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New Orleans Saints vs. San Francisco 49ers Prediction NFL in American Football

Match Analysis: New Orleans Saints vs San Francisco 49ers – Prediction

Match Details

  • Date: 2025-09-14
  • Time: 5:01 PM UTC
  • Location: Caesars Superdome

Game Overview

The San Francisco 49ers (1-0) visit the New Orleans Saints (0-1) in Week 2, with the 49ers favored as they seek to start their season 2-0 on the road, a trend linked to past deep playoff runs.

Key Factors to Consider

  • San Francisco started 1-0 with a win over Seattle, showing strong on-road performance historically vs. Saints (4-8 SU but with recent dominant tendencies). New Orleans is 0-1 with a rebuilding team under rookie coach Kellen Moore.
  • Historically, 49ers are 4-8 SU on road vs. Saints but have shown dominance in recent seasons when starting strong. ATS records favor the Saints recently, but line movement favors 49ers.
  • 49ers likely without starting QB Brock Purdy due to toe injury; backup Mac Jones expected from solid camp performances. Saints' QBs and key starters largely healthy but unproven early in season.
  • The game takes place in the Saints' home dome, but 49ers' strong road starts correlate with playoff success, adding psychological motivation. Weather not a factor (domed stadium).
  • 49ers have strong motivation to maintain early momentum and prove depth despite Purdy's injury, while Saints aim to avoid an 0-2 start amid rebuild.

Odds and Predictions

Category Odds Prediction Confidence
Moneyline New Orleans +142, San Francisco -170 San Francisco β˜…β˜…β˜…β˜…β˜† 78%
Spread New Orleans +3 -105, San Francisco -3 -115 San Francisco -3 β˜…β˜…β˜…β˜…β˜† 72%
Over/under Over 40.5 -112, Under 40.5 -108 Under 40.5 β˜…β˜…β˜…β˜†β˜† 65%

Top EV Betting Odds

Discover the best value bets based on our EV analysis.

Market EV Pick
Moneyline San Francisco 49ers -8%
Spread N/A
Over/Under Under 40.5 25%

πŸ”₯ Best Value Pick: Under 40.5 at 25% EV | Suggested Bet Size: 27.2% (Kelly Criterion)

Predicted Outcome

San Francisco 49ers to win straight up and cover the -3 spread with a final score under 40.5 points.

Predicted Score: San Francisco 23 – New Orleans 17


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New Orleans Saints vs. Arizona Cardinals Prediction NFL in American Football

Match Analysis: New Orleans Saints vs Arizona Cardinals – Prediction

Match Details

  • Date: 2025-09-07
  • Time: 5:00 PM UTC
  • Location: Caesars Superdome, New Orleans

Game Overview

The Arizona Cardinals enter as strong road favorites at -6.5 against the New Orleans Saints, who are undergoing a rebuild with a new head coach and a struggling offense. The Cardinals have a more balanced roster and optimism under head coach Jonathan Gannon. This Week 1 matchup projects Arizona to control the game pace and cover the spread.

Key Factors to Consider

  • Arizona has a 2-1 preseason record and improved offensive capabilities, while New Orleans finished 0-2-1 in preseason showing offensive struggles and defensive vulnerabilities.
  • Recent H2H data favors Arizona as the superior team given their roster stability and offensive punch, while New Orleans has faced challenges maintaining consistent results.
  • No major injury reports drastically change the outlook; however, New Orleans' key offensive players have not shown breakout performances in preseason.
  • Arizona benefits from momentum entering Week 1 with renewed expectations, while New Orleans faces pressure to restart under new coaching staff and quarterback Spencer Rattler.
  • Arizona is motivated to start the season strong as a contender, whereas New Orleans appears to be in a rebuilding phase, lowering their motivation for a Week 1 upset.

Odds and Predictions

Category Odds Prediction Confidence
Moneyline Arizona Cardinals -298, New Orleans Saints +240 Arizona Cardinals β˜…β˜…β˜…β˜…β˜† 78%
Spread Arizona Cardinals -6.5 -110, New Orleans Saints +6.5 -110 Arizona Cardinals -6.5 β˜…β˜…β˜…β˜…β˜† 74%
Over/under Over 43.5 -108, Under 43.5 -112 Under 43.5 β˜…β˜…β˜…β˜†β˜† 69%

Top EV Betting Odds

Discover the best value bets based on our EV analysis.

Market EV Pick
Moneyline Arizona Cardinals -3%
Spread N/A
Over/Under Under 43.5 17%

πŸ”₯ Best Value Pick: Under 43.5 at 17% EV | Suggested Bet Size: 19.4% (Kelly Criterion)

Predicted Outcome

Arizona Cardinals to win moneyline and cover the spread; game total under 43.5 points.

Predicted Score: Arizona Cardinals 24 – New Orleans Saints 14


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Top EV Parlay for American Football – September 7, 2025 Daily Parlay

Top EV Parlay for American Football – September 7, 2025

Game Pick Odds EV
New Orleans Saints vs. Arizona Cardinals Prediction Under 43.5 -112 17%
Jacksonville Jaguars vs. Carolina Panthers Prediction Under 46.5 -105 17%
Cleveland Browns vs. Cincinnati Bengals Prediction Under 48.5 -112 14%

Combined Odds: +600 |
Wager: $20Β β€”
Potential Payout: $139.9

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3 Pick Parlay for American Football – September 7, 2025 Daily Parlay

3 Pick Daily Parlay

Game Pick Odds (American) Confidence
Jacksonville Jaguars vs. Carolina Panthers Prediction Jacksonville Jaguars Win -185 β˜…β˜…β˜…β˜…β˜† 78% (78%)
New Orleans Saints vs. Arizona Cardinals Prediction Arizona Cardinals Win -298 β˜…β˜…β˜…β˜…β˜† 78% (78%)
Washington Commanders vs. New York Giants Prediction Washington Commanders Win -270 β˜…β˜…β˜…β˜…β˜† 76% (76%)

Parlay Odds Calculation

Combined American Odds: +182

Wager: $20 β€” Potential Payout: $56.39

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